LivoLiv supplementation improves liver health and broiler performance
Liver health plays a central role in nutrient metabolism, detoxification, lipid utilization, and overall physiological resilience in poultry production. Under intensive rearing conditions, broilers are constantly exposed to nutritional, environmental, and metabolic stressors that can compromise hepatic function and ultimately affect productive performance.
As modern poultry systems continue to push for higher efficiency and faster growth rates, maintaining optimal liver function has become increasingly important for supporting feed efficiency, nutrient utilization, metabolic balance, and bird resilience.
Why liver health matters
The liver is one of the most metabolically active organs in broilers, influencing nutrient metabolism, detoxification, immunity, and overall productive performance.
A natural polyherbal approach
Researchers evaluated the effects of dietary supplementation with a natural polyherbal mixture (PHM), commercially known as LivoLiv™ (Nuproxa Switzerland Ltd.), on broiler growth performance and hepatic metabolic indicators.
The product is rich in quercetin and andrographolides, compounds known for their antioxidant and hepatoprotective properties. These bioactive molecules are increasingly attracting attention in poultry nutrition because of their potential to support metabolic function and help birds cope with physiological stress.
Natural phytogenic solutions are gaining relevance in poultry nutrition as tools to support liver function, oxidative balance, and metabolic resilience.
Study design
The study included 540 one-day-old male Cobb500 broilers, randomly assigned to three dietary treatments:
- CON: Basal diet
- PHM250: Basal diet + 250 g/t of LivoLiv™
- PHM500: Basal diet + 500 g/t of LivoLiv™
Each treatment consisted of 10 replicates with 18 birds per replicate. Researchers recorded body weight (BW), feed intake (FI), and feed conversion ratio (FCR) weekly throughout the trial.
At 34 days of age, blood samples were collected for biochemical evaluation of hepatic and lipid metabolic indicators.
Research focus
The trial aimed to evaluate whether phytogenic supplementation could improve both productive performance and liver-associated metabolic indicators in broilers.
Improved growth performance
Results showed that supplementation with the polyherbal mixture improved growth performance compared with the control group.
At 34 days:
- PHM500 birds achieved the highest body weight
- PHM250 birds achieved the best feed conversion ratio
Body weight values reached:
- CON: 2312 g
- PHM250: 2344 g
- PHM500: 2378 g
Meanwhile, the best FCR was observed in the PHM250 group:
- CON: 1.482
- PHM250: 1.448
- PHM500: 1.478
LivoLiv™ supplementation improved both growth performance and feed efficiency, demonstrating its potential value in commercial broiler production.
Hepatic metabolism and physiological response
Birds receiving the higher supplementation level (PHM500) also showed increases in serum markers associated with hepatic activity and lipid metabolism, including:
- AST
- ALT
- Albumin
- Cholesterol
Importantly, researchers indicated that these changes remained within physiological ranges and were interpreted as signs of enhanced hepatic metabolic activity rather than liver damage.
According to the authors, these responses may reflect:
- Improved hepatocellular metabolism
- Enhanced nutrient utilization
- Better lipid mobilization
- Greater metabolic resilience
Metabolic perspective
Supporting hepatic metabolism may help broilers better cope with production stress while improving nutrient efficiency and performance.
The role of quercetin and andrographolides
The beneficial effects observed in this study may be linked to the biological properties of the active compounds present in the polyherbal mixture.
Quercetin is widely recognized for its antioxidant properties and ability to modulate oxidative stress and inflammatory pathways. Meanwhile, andrographolides have been associated with hepatoprotective and immunomodulatory effects.
Together, these compounds may contribute to:
- Reduced oxidative stress
- Improved liver resilience
- Enhanced nutrient metabolism
- Better physiological adaptation under intensive production conditions
Phytogenic compounds are increasingly being explored as nutritional tools to support metabolism, oxidative balance, and resilience in poultry systems.
Practical implications for poultry nutrition
As poultry production systems continue to evolve, maintaining liver health becomes increasingly important for sustaining productivity and efficiency. Nutritional interventions that support hepatic function may help producers:
- Improve feed utilization
- Support bird resilience under stress
- Maintain productive performance
- Optimize metabolic efficiency
The findings from this study suggest that natural phytogenic supplementation may represent a valuable strategy for supporting both performance and liver-associated metabolic processes in broilers.
LivoLiv™ supplementation improved hepatic function and metabolic resilience in broilers, supporting better liver health and productive performance.
Conclusion
The study demonstrated that dietary supplementation with LivoLiv™ positively influenced growth performance and hepatic metabolic indicators in broilers.
These findings reinforce the growing importance of nutritional strategies aimed at supporting liver health and metabolic resilience under modern intensive poultry production systems.