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Poultry and livestock production are vital to global food security, nutrition, and rural livelihoods. As the demand for meat, milk, and eggs continues to rise, producers are increasingly focused on improving feed efficiency, animal performance, and sustainable production systems.
Choline, an essential component classified as a water-soluble compound similar to vitamin B, plays a critical role in fat metabolism, liver health, cellular integrity, and growth performance.
Optimizing choline nutrition is essential for supporting metabolic efficiency, liver function, growth performance, and sustainable poultry production.
Poultry birds have a limited ability to synthesize sufficient choline; therefore, Choline Chloride 60% is commonly added to poultry diets.
Poultry birds have a limited ability to synthesize sufficient choline; therefore, Choline Chloride 60% (CC 60%) is commonly added to poultry diets. However, conventional supplementation through synthetic sources presents several limitations.
Synthetic choline chloride, being a petrochemical byproduct, raises environmental concerns because it is highly hygroscopic and can accelerate oxidation, leading to loss of vitamins in feed. Its corrosive nature can damage feed enzymes and create handling challenges.
Additionally, it may contribute to trimethylamine formation in the intestinal tract of broilers, impacting the gut environment.
Synthetic choline chloride presents challenges related to environmental concerns, hygroscopicity, oxidation, corrosion, handling, and supply stability.
Understanding the requirements in poultry diet and the challenges associated with synthetic choline, Kolin Plus FC, a natural, safe, and effective solution, was formulated.
Kolin Plus FC, a phytogenic solution formulated by M/s Natural Remedies Pvt Ltd, based in Bengaluru, India, is developed by the synergistic blend of Acacia nilotica and Curcuma longa plant parts.
Kolin Plus FC is positioned as a greener phytogenic alternative to conventional synthetic choline chloride.
Key components: Catechins, polyphenols, tannins.
Function: Helps reduce hepatic fat accumulation, supports triglyceride mobilization from the liver, restores normal liver tissue architecture, and provides antioxidant protection that supports growth and feed efficiency.
Key components: Curcuminoids (Curcumin).
Function: Supports regulation of lipid metabolism, helps prevent fatty liver, promotes hepatocellular protection, reduces inflammation, and enhances overall liver efficiency during metabolic stress.
The phytogenic blend in Kolin Plus FC supports lipid metabolism, liver protection, antioxidant defense, and feed efficiency.
To prove the effectiveness of Kolin Plus FC, several studies have been conducted to date, which prove that Kolin Plus FC is as effective as synthetic alternatives.
A study was conducted with Cobb500 broiler chicks to evaluate the impact of synthetic and natural choline supplementation on broiler production performance and liver health.
The trial compared conventional synthetic choline chloride with Kolin Plus FC, a phytogenic solution developed by M/s Natural Remedies Pvt Ltd, designed to support efficient fat metabolism and growth performance in broilers.
Broilers supplemented with Kolin Plus FC achieved higher body weight performance compared to birds receiving synthetic choline chloride, demonstrating its effectiveness as a natural solution for supporting optimal growth in poultry production.
At 42 days, broilers supplemented with Kolin Plus FC achieved a final body weight of 2.97 kg, compared with 2.93 kg for synthetic choline chloride and 2.89 kg for the control group.
Figure 1. Performance of broilers at 42 days comparing final body weight across three supplementation groups: a control group without supplemental choline, a group supplemented with synthetic choline chloride (CC 60%), and a group supplemented with Kolin Plus FC.
Broilers supplemented with Kolin Plus FC demonstrated a better feed conversion ratio compared to both the control group and birds supplemented with synthetic choline chloride, indicating improved feed efficiency and better utilization of nutrients for growth.
Kolin Plus FC improved feed conversion ratio, reaching 1.62 compared with 1.66 in the control group and 1.71 in the synthetic choline chloride group.
Figure 2. Performance of broilers at 42 days comparing feed conversion ratio (FCR) across three supplementation groups: a control group without supplemental choline, a group supplemented with synthetic choline chloride (CC 60%), and a group supplemented with Kolin Plus FC.
Broilers supplemented with Kolin Plus FC demonstrated a reduction in hepatic steatosis score (SS), indicating reduced fat accumulation in the liver and improved liver health compared to the control group and synthetic choline chloride supplementation.
Kolin Plus FC reduced the hepatic steatosis score to 2.25, compared with 3.31 in the control group and 2.97 in the synthetic choline chloride group.
Figure 3. Performance of broilers at 42 days comparing Hepatic Steatosis Score (HSS) across three supplementation groups: a control group without supplemental choline, a group supplemented with synthetic choline chloride (CC 60%), and a group supplemented with Kolin Plus FC.
Note: Means followed by different letters in the same column differ significantly (Tukey test, P<0.05).
Maintaining consistent egg production and egg quality throughout the laying cycle is essential for profitable layer operations. As birds age, a gradual decline in laying persistence and egg quality parameters is commonly observed, affecting overall production efficiency.
Kolin Plus FC supports sustained egg production by helping layer birds maintain production consistency over an extended laying period. Birds supplemented with Kolin Plus FC demonstrate improved laying persistence, enabling better maintenance of production performance as the flock advances in age.
Along with supporting production, Kolin Plus FC also helps maintain key egg quality parameters important for market acceptance and hatchability performance. Parameters such as shell strength, shell thickness, egg density, and internal egg quality remain stable, contributing to the production of high-quality eggs throughout the production cycle.
By supporting both egg production and egg quality simultaneously, Kolin Plus FC helps optimize overall layer performance and contributes to improved production efficiency in commercial layer operations.
Kolin Plus FC offers a smarter and more sustainable approach to choline nutrition in animal feed.
With advantages such as uniform particle size for better mixing, compatibility with vitamin and mineral premixes, effective performance at low inclusion levels, non-hygroscopic properties, non-corrosive handling and residue-free supplementation, it addresses many limitations associated with conventional choline chloride.
Kolin Plus FC is described as highly compatible with vitamin and mineral premixes, non-hygroscopic, non-corrosive, residue-free, uniform in particle size, and active at low doses.
Beyond nutritional performance, Kolin Plus FC also supports environmental responsibility, having contributed to the reduction of 1 billion+ carbon footprints.
By combining efficiency, safety, and sustainability, Kolin Plus FC stands out as a future-ready solution for modern feed production.
Kolin Plus FC provides a greener alternative to choline chloride, supporting poultry performance, liver health, feed efficiency, egg quality, and sustainable feed production.
*Dosage may vary depending on region, diet, and species.
Ramalho de Lima M, Kaneko IN, de Lima AV, de Melo LN, de Lima MC, de Brito ANEF, et al. (2024). Choline supplementation: Impact on broiler chicken performance, steatosis, and economic viability from 1 to 42 days. PLoS ONE 19(3): e0295488. https://doi.org/10.1371/journal.pone.0295488
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